I was thrilled when my mother bought a 2002 A6, she was 84 at the time and I knew I would be doing most or all of the driving. I always liked Audi's. She got the plain vanilla 2.8. Nice car, does everything well. Sure can't fault the interior in any way, and has a trunk big enough to house a family of four. My only complaint is the fuel capacity. It's fine for highway driving but seems a little small to me because the car is used mainly around town and the A6 doesn't get great mileage in city driving.
I really wanted something a little more sporty, but that wouldn't be appropriate for her. I wanted an A4 turbo, which is a little more tightly wound than the regular A6. She (under 5' tall) claimed the A4 was "too small." Generational thing I guess.
I'm thinking the twin turbo is a more sport oriented car. Tighter suspension, etc. Not to fault the regular A6, I'm sure it will be fun if I ever get it on the twisties.
Haven't had any problems with the Audi at all, though there have been several minor recalls. I do suppose the rice burners will be more reliable in the long run. Watch out for the Toyota's though. I remember hearing of serious engine problems that Toyota was not willing to take care of. Not sure which model or engine, I think it was related to a specific engine.
Now This Is Just Plain StupidDid you know that California pbutted a law that allows those Harley Mouth-breathers with straight pipes to wear earplugs while riding? Check out CVC 27400 (d): 27400. A...
I'd take extended drives in all the models you list and decide by how they feel to you. They are surely all good cars.